Which organization is a multiagency coordination center generally staffed by ESFs in anticipation of or immediately following an incident?

The organization that serves as a multiagency coordination center generally staffed by Emergency Support Functions (ESFs) in anticipation of or immediately following an incident is the Joint Field Office (JFO).

A Joint Field Office (JFO) is a temporary federal facility that provides a central location for the coordination of federal, state, tribal, and local governments, as well as private-sector and nongovernmental organizations, ensuring an integrated approach to incident management and response.

From the perspective of personnel involved in emergency management and response, the Joint Field Office (JFO) is recognized for its role in facilitating seamless communication and resource allocation among various agencies and organizations.

Source: https://training.fema.gov/emiweb/is/is800d/english/instructor%20guide/el0800.d%20ig.pdf